Chromosomal instability: a key driver in glioma pathogenesis and progression

Chromosomal instability: a key driver in glioma pathogenesis and progression

Abstract Chromosomal instability (CIN) is a pivotal factor in gliomas, contributing to their complexity, progression, and therapeutic challenges. CIN, characterized by frequent genomic alterations during mitosis, leads to genetic abnormalities and impacts cellular functions. This instability results...

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Bibliographic Details
Main Authors: Adele Mazzoleni, Wireko Andrew Awuah, Vivek Sanker, Hareesha Rishab Bharadwaj, Nicholas Aderinto, Joecelyn Kirani Tan, Helen Ye Rim Huang, Jeisun Poornaselvan, Muhammad Hamza Shah, Oday Atallah, Aya Tawfik, Mohamed Elsayed Abdelmeguid Elsayed Elmanzalawi, Sama Hesham Ghozlan, Toufik Abdul-Rahman, Jeremiah Adepoju Moyondafoluwa, Athanasios Alexiou, Marios Papadakis
Format: Article
Language:English
Published: BMC 2024-09-01
Series:European Journal of Medical Research
Subjects:
Chromosomal instability
Gliomas
Neuro-oncology
Molecular genetics
Online Access:https://doi.org/10.1186/s40001-024-02043-8

Internet

https://doi.org/10.1186/s40001-024-02043-8

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