Graded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator

Graded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator

<p>Abstract</p> <p>Background</p> <p>Currently, the step-wise integration of tet-dependent transactivator and tet-responsive expression unit is considered to be the most promising tool to achieve stable tet-controlled gene expression in cell populations. However, disadv...

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Bibliographic Details
Main Authors: Heinz Niels, Hennig Katharina, Loew Rainer
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Biotechnology
Subjects:
Tet-controlled gene expression
Transactivator concentration
Threshold response
Self-contained
Autoregulated
Online Access:http://www.biomedcentral.com/1472-6750/13/5

Internet

http://www.biomedcentral.com/1472-6750/13/5

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