Carbamazepine Increases the Risk of Sudden Cardiac Arrest by a Reduction of the Cardiac Sodium Current

Carbamazepine Increases the Risk of Sudden Cardiac Arrest by a Reduction of the Cardiac Sodium Current

Aim: To assess the risk of sudden cardiac arrest (SCA) associated with the use of carbamazepine (CBZ) and establish the possible underlying cellular electrophysiological mechanisms.Methods: The SCA risk association with CBZ was studied in general population cohorts using a case–control design (n = 5...

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Bibliographic Details
Main Authors: Lixia Jia, Talip E. Eroglu, Ronald Wilders, Arie O. Verkerk, Hanno L. Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
anti-epileptic drugs
sudden cardiac arrest
risk association
cardiomyocytes
sodium current
action potentials
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.891996/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.891996/full

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