Crystal Structure of an Active Site Mutant Form of IRG1 from <i>Bacillus subtilis</i>
Immune-responsive gene1 (IRG1), an enzyme that is overexpressed during immune reactions, catalyzes the production of itaconate from cis-aconitate. Itaconate is a multifunctional immuno-metabolite that displays antibacterial and antiviral activities. The recent resolution of its structure has enabled...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Crystals |
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| Online Access: | https://www.mdpi.com/2073-4352/11/4/350 |