High levels of monocytic myeloid-derived suppressor cells are associated with favorable outcome in patients with pneumonia and sepsis with multi-organ failure

High levels of monocytic myeloid-derived suppressor cells are associated with favorable outcome in patients with pneumonia and sepsis with multi-organ failure

Abstract Background Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells with immunosuppressive functions sub-classified into monocytic and polymorphonuclear MDSCs (M-MDSCs and PMN-MDSCs). Clinical studies reported increased levels of MDSCs that were associated with poor outcome in se...

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Bibliographic Details
Main Authors: Irene T. Schrijver, Eleni Karakike, Charlotte Théroude, Pétra Baumgartner, Alexandre Harari, Evangelos J. Giamarellos-Bourboulis, Thierry Calandra, Thierry Roger
Format: Article
Language:English
Published: SpringerOpen 2022-02-01
Series:Intensive Care Medicine Experimental
Subjects:
Sepsis
Pneumonia
Infection
Multi-organ dysfunction
Myeloid-derived suppressor cells
Critically ill
Online Access:https://doi.org/10.1186/s40635-022-00431-0

Internet

https://doi.org/10.1186/s40635-022-00431-0

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