Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation

Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation

Abstract Background Synthetic amorphous silica nanoparticles (SAS-NPs) are widely employed in pharmaceutics, cosmetics, food and concretes. Workers and the general population are exposed daily via diverse routes of exposure. SAS-NPs are generally recognized as safe (GRAS) by the Food and Drug Admini...

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Bibliographic Details
Main Authors: Éléonore Guillet, Émilie Brun, Céline Ferard, Kévin Hardonnière, Myriam Nabhan, François-Xavier Legrand, Marc Pallardy, Armelle Biola-Vidamment
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Particle and Fibre Toxicology
Subjects:
Amorphous silica
Nanoparticles
Dendritic cells
Syk
Lipid rafts
Src kinases
Online Access:https://doi.org/10.1186/s12989-023-00527-9

Internet

https://doi.org/10.1186/s12989-023-00527-9

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