Immunologic evaluation and validation of methods using synthetic peptides derived from Mycobacterium tuberculosis for the diagnosis of tuberculosis infection

Immunologic evaluation and validation of methods using synthetic peptides derived from Mycobacterium tuberculosis for the diagnosis of tuberculosis infection

The goal of this study was to demonstrate the usefulness of an enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of pulmonary tuberculosis (PTB) and extrapulmonary TB (EPTB). This assay used 20 amino acid-long, non-overlapped synthetic peptides that spanned the complete Mycobacterium t...

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Bibliographic Details
Main Authors: Zaida Araujo, Francesca Giampietro, María de los Angeles Bochichio, Andrea Palacios, Jenifer Dinis, Jaime Isern, Jacobus Henry de Waard, Elsa Rada, Rafael Borges, Carlos Fernández de Larrea, Angel Villasmil, Magnolia Vanegas, Jose Antonio Enciso-Moreno, Manuel Alfonso Patarroyo
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-04-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
pulmonary tuberculosis
extrapulmonary tuberculosis
synthetic peptide
ESAT-6 antigen
Ag85A antigen
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000200131&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000200131&lng=en&tlng=en

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