Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner

Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner

The acknowledgment that pollutants might influence the epigenome raises serious concerns regarding their long-term impact on the development of chronic diseases. The herbicide glyphosate has been scrutinized for an impact on cancer incidence, but reports demonstrate the difficulty of linking estimat...

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Bibliographic Details
Main Authors: Manon Duforestel, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Joséphine Briand, Christophe Olivier, Jean-Sébastien Frenel, François M. Vallette, Sophie A. Lelièvre, Pierre-François Cartron
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
ten-eleven translocation
breast cancer
hypomethylation
epigenetic mark
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00885/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00885/full

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