Anti-HER-2 therapy following severe trastuzumab-induced cardiac toxicity

The human epidermal growth factor receptor 2 (HER2) is overexpressed in 25%–30% of breast cancer patients. Anti-HER2 therapies have changed the aggressive course of HER2+ breast cancer. In spite of the therapeutic benefits, their cardiotoxicities are major concerns, especially when used concurrently...

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Bibliographic Details
Main Authors: Ibrahim Sadek, Mark Keaton, Nita J. Maihle, Shou-Ching Tang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2017-09-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304217300466