Computational identification of 4-carboxyglutamate sites to supplement physiological studies using deep learning

Abstract In biological systems, Glutamic acid is a crucial amino acid which is used in protein biosynthesis. Carboxylation of glutamic acid is a significant post-translational modification which plays important role in blood coagulation by activating prothrombin to thrombin. Contrariwise, 4-carboxy-...

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Bibliographic Details
Main Authors: Sheraz Naseer, Rao Faizan Ali, Suliman Mohamed Fati, Amgad Muneer
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03895-4