A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry

A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry

Vicinal diols are important signaling metabolites of various inflammatory diseases, and some of them are potential biomarkers for some diseases. Utilizing the rapid reaction between diol and 6-bromo-3-pyridinylboronic acid (BPBA), a selective and sensitive approach was established to profile these v...

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Bibliographic Details
Main Authors: Debin Wan, Christophe Morisseau, Bruce D. Hammock, Jun Yang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
vicinal diols
epoxide hydrolase
double precursor ion scan
online post-column derivatization
Online Access:https://www.mdpi.com/1420-3049/27/1/283

Internet

https://www.mdpi.com/1420-3049/27/1/283

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