Long-Term, Low-Dose Exposure to Microcystin-LR Does not Cause or Increase the Severity of Liver Disease in Rodents

Long-Term, Low-Dose Exposure to Microcystin-LR Does not Cause or Increase the Severity of Liver Disease in Rodents

Background: Acute exposure to high concentrations of microcystin-LR (MC-LR) can cause significant hepatocyte injury. Aim. To document the effects of long-term, low-dose MC-LR exposure on hepatic inflammation and fibrosis in mice with healthy and diseased livers. Material and methods: Male CD1 mice (...

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Bibliographic Details
Main Authors: Meaghan Labine, Yuewen Gong, Gerald Y. Minuk
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Annals of Hepatology
Subjects:
Cyanobacteria
Blue-green algae
Cyanotoxins
Microcystins
Hepatic fibrosis
Cirrhosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119304648

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http://www.sciencedirect.com/science/article/pii/S1665268119304648

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