Immunization of Rabbits with a Quadrivalent Shigella Bioconjugate Vaccine Induces Functional Antibodies Reactive with Shigella Isolates from Kenya

Immunization of Rabbits with a Quadrivalent Shigella Bioconjugate Vaccine Induces Functional Antibodies Reactive with Shigella Isolates from Kenya

ABSTRACT Diarrheal diseases are a leading cause of global morbidity and mortality, disproportionately affecting children in resource-limited settings. Although improvements in hygiene and access to clean water are helpful, vaccines are considered essential due to the low infectious dose of Shigella...

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Bibliographic Details
Main Authors: Elizabeth A. Odundo, Hailey P. Weerts, Lillian Musila, Lilian Ogonda, Anita M. Dreyer, Joerg Schneider, Paula Carranza, Robert W. Kaminski
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mSphere
Subjects:
Shigella
bioconjugate vaccine
preclinical
antibody
functional
Online Access:https://journals.asm.org/doi/10.1128/msphere.01020-21

Internet

https://journals.asm.org/doi/10.1128/msphere.01020-21

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