Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice

Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice

Diabetes is one of the well-established risk factors of stroke and is associated with a poor outcome in patients with stroke. Previous studies have shown that the expression of neuron restrictive silencer factor (NRSF) is elevated in diabetes as well as ischemic stroke. However, the role of NRSF in...

Full description

Bibliographic Details
Main Authors: Cheng-Feng He, Wen-Jiao Xue, Xiao-Die Xu, Jian-Tao Wang, Xin-Ru Wang, Yi Feng, Hou-Guang Zhou, Jing-Chun Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Neurology
Subjects:
NRSF/REST
diabetes
ischemic stroke
brain injury
NRP-1/VEGF
revascularization
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.869220/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.869220/full

Similar Items