Recapitulating human ovarian aging using random walks

Mechanism(s) that control whether individual human primordial ovarian follicles (PFs) remain dormant, or begin to grow, are all but unknown. One of our groups has recently shown that activation of the Integrated Stress Response (ISR) pathway can slow follicular granulosa cell proliferation by activa...

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Bibliographic Details
Main Authors: Joshua Johnson, John W. Emerson, Sean D. Lawley
Format: Article
Language:English
Published: PeerJ Inc. 2022-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/13941.pdf