Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Abstract Tau tubulin kinase 1 and 2 (TTBK1/2) are highly homologous kinases that are expressed and mediate disease-relevant pathways predominantly in the brain. Distinct roles for TTBK1 and TTBK2 have been delineated. While efforts have been devoted to characterizing the impact of TTBK1 inhibition i...

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Bibliographic Details
Main Authors: Frances M. Bashore, Ariana B. Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran, Jeffery L. Smith, David H. Drewry, Adriana S. Beltran, Alison D. Axtman
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32854-4

Internet

https://doi.org/10.1038/s41598-023-32854-4

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