Low-Dose Estrogens as Neuroendocrine Modulators in Functional Hypothalamic Amenorrhea (FHA): The Putative Triggering of the Positive Feedback Mechanism(s)

Low-Dose Estrogens as Neuroendocrine Modulators in Functional Hypothalamic Amenorrhea (FHA): The Putative Triggering of the Positive Feedback Mechanism(s)

Functional hypothalamic amenorrhea (FHA) is a non-organic reversible chronic endocrine disorder characterized by an impaired pulsatile secretion of the gonadotropin-releasing hormone (GnRH) from the hypothalamus. This impaired secretion, triggered by psychosocial and metabolic stressors, leads to an...

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Bibliographic Details
Main Authors: Christian Battipaglia, Tabatha Petrillo, Elisa Semprini, Francesco Ricciardiello, Maria Laura Rusce, Greta Prampolini, Fedora Ambrosetti, Alessandra Sponzilli, Alessandro D. Genazzani
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
functional hypothalamic amenorrhea
opioids
estriol
estradiol
positive feedback
stress
Online Access:https://www.mdpi.com/2227-9059/11/6/1763

Internet

https://www.mdpi.com/2227-9059/11/6/1763

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