Zinc finger and SCAN domain containing 1, ZSCAN1, is a novel stemness-related tumor suppressor and transcriptional repressor in breast cancer targeting TAZ

Zinc finger and SCAN domain containing 1, ZSCAN1, is a novel stemness-related tumor suppressor and transcriptional repressor in breast cancer targeting TAZ

IntroductionCancer stem cells (CSCs) targeted therapy holds the potential for improving cancer management; identification of stemness-related genes in CSCs is necessary for its development.MethodsThe Cancer Genome Atlas (TCGA) and the Molecular Taxonomy of Breast Cancer International Consortium (MET...

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Bibliographic Details
Main Authors: Jian Chu, Yunzhe Li, Misi He, Hui Zhang, Lingling Yang, Muyao Yang, Jingshu Liu, Chenxi Cui, Liquan Hong, Xingchi Hu, Lei Zhou, Tangya Li, Changchun Li, Huiwen Fan, Guoqin Jiang, Tingyuan Lang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
ZSCAN1
breast cancer
stemness
tumor suppressor
transcriptional repressor
TAZ
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1041688/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1041688/full

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