Investigating Carvedilol’s Repurposing for the Treatment of Non-Small Cell Lung Cancer via Aldehyde Dehydrogenase Activity Modulation in the Presence of β-Adrenergic Agonists

Investigating Carvedilol’s Repurposing for the Treatment of Non-Small Cell Lung Cancer via Aldehyde Dehydrogenase Activity Modulation in the Presence of β-Adrenergic Agonists

Repurposing existing drugs appears to be a potential solution for addressing the challenges in the treatment of non-small cell lung cancer (NSCLC). β-adrenoceptor antagonist drugs (β-blockers) have tumor-inhibiting effects, making them promising candidates for potential NSCLC treatment. This study i...

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Bibliographic Details
Main Authors: Balqis A. Ikhmais, Alaa M. Hammad, Osama H. Abusara, Lama Hamadneh, Hamza Abumansour, Qasem M. Abdallah, Ali I. M. Ibrahim, Lina Elsalem, Mariam Awad, Rahaf Alshehada
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Current Issues in Molecular Biology
Subjects:
repurposing
lung cancer
β-blockers
carvedilol
β-agonists
aldehyde dehydrogenase
Online Access:https://www.mdpi.com/1467-3045/45/10/505

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https://www.mdpi.com/1467-3045/45/10/505

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