Generation of Oxygen Free Radicals by Proflavine: Implication in Protein Degradation

Generation of Oxygen Free Radicals by Proflavine: Implication in Protein Degradation

Show other versions (1)

Proflavine, an acridine dye, is a known DNA intercalating agent. In the present study, we show that proflavine alone on photoillumination can generate reactive oxygen species (ROS). These proflavine-derived ROS cause damage to proteins, and this effect is enhanced when the divalent metal ion Cu (II)...

Full description

Bibliographic Details
Main Authors: Mansour K.M. Gatasheh, Kannan Subbaram, Hemalatha Kannan, Imrana Naseem
Format: Article
Language:English
Published: Bogor Agricultural University 2018-03-01
Series:Hayati Journal of Biosciences
Subjects:
bovine serum albumin
photoillumination
proflavine
protein degradation
reactive oxygen species
Online Access:https://journal.ipb.ac.id/index.php/hayati/article/view/20802

Internet

https://journal.ipb.ac.id/index.php/hayati/article/view/20802

Similar Items