2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study

2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study

Nitro-containing compounds are a well-known class of anti-infective agents, especially in the field of anti-parasitic drug discovery. HAT or sleeping sickness is a neglected tropical disease caused by a protozoan parasite, <i>Trypanosoma brucei</i>. Following the approval of fexinidazole...

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Bibliographic Details
Main Authors: Alireza Mousavi, Parham Foroumadi, Zahra Emamgholipour, Pascal Mäser, Marcel Kaiser, Alireza Foroumadi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
nitroimidazole
1,3,4-thiadiazole
sleeping sickness
<i>Trypanosoma brucei</i>
Online Access:https://www.mdpi.com/1420-3049/27/17/5559

Internet

https://www.mdpi.com/1420-3049/27/17/5559

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