Multi-regional alterations in glucose and purine metabolic pathways in the Parkinson’s disease dementia brain

Abstract Parkinson’s disease (PD) is one of the most common neurodegenerative diseases, most commonly characterised by motor dysfunction, but also with a high prevalence of cognitive decline in the decades following diagnosis—a condition known as Parkinson’s disease dementia (PDD). Although several...

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Bibliographic Details
Main Authors: Melissa Scholefield, Stephanie J. Church, George Taylor, David Knight, Richard D. Unwin, Garth J. S. Cooper
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00488-y