Incidence and impact of brain metastasis in patients with hereditary BRCA1 or BRCA2 mutated invasive breast cancer

Abstract Patients with hereditary mutations in BRCA1 or BRCA2 (gBRCA1/2) and breast cancer have distinct tumor biology, and encompass a predilection for brain metastasis (BM). We looked into baseline risk of BMs among gBRCA1/2 patients. Patients with gBRCA1/2, stage I-III invasive breast cancer seen...

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Bibliographic Details
Main Authors: Haven R. Garber, Akshara Singareeka Raghavendra, Michael Lehner, Wei Qiao, Angelica M. Gutierrez-Barrera, Debu Tripathy, Banu Arun, Nuhad K. Ibrahim
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-022-00407-z