Gram-positive anaerobic cocci guard skin homeostasis by regulating host-defense mechanisms

Summary: In atopic dermatitis (AD), chronic skin inflammation is associated with skin barrier defects and skin microbiome dysbiosis including a lower abundance of Gram-positive anaerobic cocci (GPACs). We here report that, through secreted soluble factors, GPAC rapidly and directly induced epidermal...

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Bibliographic Details
Main Authors: Danique A. van der Krieken, Gijs Rikken, Thomas H.A. Ederveen, Patrick A.M. Jansen, Diana Rodijk-Olthuis, Luca D. Meesters, Ivonne M.J.J. van Vlijmen-Willems, Bram van Cranenbroek, Renate G. van der Molen, Joost Schalkwijk, Ellen H. van den Bogaard, Patrick L.J.M. Zeeuwen
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223005606