Identifying the Involvement of Pro-Inflammatory Signal in Hippocampal Gene Expression Changes after Experimental Ischemia: Transcriptome-Wide Analysis

Identifying the Involvement of Pro-Inflammatory Signal in Hippocampal Gene Expression Changes after Experimental Ischemia: Transcriptome-Wide Analysis

Acute cerebral ischemia induces distant inflammation in the hippocampus; however, molecular mechanisms of this phenomenon remain obscure. Here, hippocampal gene expression profiles were compared in two experimental paradigms in rats: middle cerebral artery occlusion (MCAO) and intracerebral administ...

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Bibliographic Details
Main Authors: Galina T. Shishkina, Natalia V. Gulyaeva, Dmitriy A. Lanshakov, Tatyana S. Kalinina, Mikhail V. Onufriev, Yulia V. Moiseeva, Ekaterina V. Sukhareva, Vladimir N. Babenko, Nikolay N. Dygalo
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
RNA-seq
differentially expressed genes
middle cerebral artery occlusion
lipopolysaccharide
hippocampus
Online Access:https://www.mdpi.com/2227-9059/9/12/1840

Internet

https://www.mdpi.com/2227-9059/9/12/1840

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