Exosomes Derived from Mesenchymal Stem Cells Rescue Myocardial Ischaemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy Via AMPK and Akt Pathways

Exosomes Derived from Mesenchymal Stem Cells Rescue Myocardial Ischaemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy Via AMPK and Akt Pathways

Background/Aims: Reperfusion after an ischaemic insult might cause infarct extension. Mesenchymal stem cell (MSC)-derived exosomes could attenuate myocardial remodelling in animal models of myocardial ischaemia reperfusion injury (MIRI), and the present study aimed to explore the related mechanisms....

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Bibliographic Details
Main Authors: Liang Liu, Xian Jin, Cui-Fen Hu, Rong Li, Zhong’e Zhou, Cheng-Xing Shen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mesenchymal stem cell
Cardiomyocytes
Myocardial ischaemia/reperfusion Injury
Exosomes
Autophagy
Online Access:http://www.karger.com/Article/FullText/480317

Internet

http://www.karger.com/Article/FullText/480317

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