Influence of sex, age and diabetes on brain transcriptome and proteome modifications following cerebral ischemia

Abstract Ischemic stroke is a major cause of death and disability worldwide. Translation into the clinical setting of neuroprotective agents showing promising results in pre-clinical studies has systematically failed. One possible explanation is that the animal models used to test neuroprotectants d...

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Bibliographic Details
Main Authors: Laura Ramiro, Júlia Faura, Alba Simats, Paula García-Rodríguez, Feifei Ma, Luna Martín, Francesc Canals, Anna Rosell, Joan Montaner
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-023-00775-7