Integrative understanding of hypoxic pulmonary vasoconstriction using in vitro models: from ventilated/perfused lung to single arterial myocyte

Integrative understanding of hypoxic pulmonary vasoconstriction using in vitro models: from ventilated/perfused lung to single arterial myocyte

Contractile response of a pulmonary artery (PA) to hypoxia (hypoxic pulmonary vasoconstriction; HPV) is a unique physiological reaction. HPV is beneficial for the optimal distribution of blood flow to differentially ventilated alveolar regions in the lung, thereby preventing systemic hypoxemia. Nume...

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Bibliographic Details
Main Authors: Hae Young Yoo, Su Jung Park, Hae Jin Kim, Woo Kyung Kim, Sung Joon Kim
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Integrative Medicine Research
Subjects:
hypoxic pulmonary vasoconstriction
K+ channel
oxygen
patch clamp
pulmonary artery
smooth muscle
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422014000468

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http://www.sciencedirect.com/science/article/pii/S2213422014000468

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