Approaches towards Structures of Y Receptors, Examples of Human G-Protein Coupled Receptors, by Solution NMR
Despite recent advances no solution structure for a true G-protein coupled receptor (GPCR) is available today due to biochemical and spectroscopic problems. Herein we review our attempts to obtain assignments of GPCRs based on fragments comprising 2-3 transmembrane helices. The fragments a...
Main Authors: | , |
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Format: | Article |
Language: | deu |
Published: |
Swiss Chemical Society
2012-10-01
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Series: | CHIMIA |
Subjects: | |
Online Access: | https://www.chimia.ch/chimia/article/view/5287 |