Emergent properties of tumor microenvironment in a real-life model of multicell tumor spheroids.

Multicellular tumor spheroids are an important in vitro model of the pre-vascular phase of solid tumors, for sizes well below the diagnostic limit: therefore a biophysical model of spheroids has the ability to shed light on the internal workings and organization of tumors at a critical phase of thei...

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Bibliographic Details
Main Authors: Edoardo Milotti, Roberto Chignola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994713?pdf=render