Structural comparisons reveal diverse binding modes between nucleosome assembly proteins and histones

Abstract Nucleosome assembly proteins (NAPs) are histone chaperones that play a central role in facilitating chromatin assembly/disassembly which is of fundamental importance for DNA replication, gene expression regulation, and progression through the cell cycle. In vitro, NAPs bind to the core hist...

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Bibliographic Details
Main Authors: Jasmita Gill, Anuj Kumar, Amit Sharma
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-022-00452-9