Multivariate Analytical Approaches to Identify Key Molecular Properties of Vehicles, Permeants and Membranes That Affect Permeation through Membranes

Multivariate Analytical Approaches to Identify Key Molecular Properties of Vehicles, Permeants and Membranes That Affect Permeation through Membranes

There has been considerable recent interest in employing computer models to investigate the relationship between the structure of a molecule and its dermal penetration. Molecular permeation across the epidermis has previously been demonstrated to be determined by a number of physicochemical properti...

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Bibliographic Details
Main Authors: Omaima N. Najib, Stewart B. Kirton, Gary P. Martin, Michelle J. Botha, Al-Sayed Sallam, Darragh Murnane
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
PCA
QSPR
permeability
membrane interaction
oily vehicle
enhancer of drug penetration
Online Access:https://www.mdpi.com/1999-4923/12/10/958

Internet

https://www.mdpi.com/1999-4923/12/10/958

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