An Integrated View of Deubiquitinating Enzymes Involved in Type I Interferon Signaling, Host Defense and Antiviral Activities

An Integrated View of Deubiquitinating Enzymes Involved in Type I Interferon Signaling, Host Defense and Antiviral Activities

Viral infectious diseases pose a great challenge to human health around the world. Type I interferons (IFN-Is) function as the first line of host defense and thus play critical roles during virus infection by mediating the transcriptional induction of hundreds of genes. Nevertheless, overactive cyto...

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Bibliographic Details
Main Authors: Guanghui Qian, Liyan Zhu, Gen Li, Ying Liu, Zimu Zhang, Jian Pan, Haitao Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
deubiquitinating enzymes
type I IFN signaling
ubiquitin
virus infection
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.742542/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.742542/full

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