Impact of SARS-CoV-2 Mutations on PCR Assay Sequence Alignment

Impact of SARS-CoV-2 Mutations on PCR Assay Sequence Alignment

Real-time reverse transcription polymerase chain reaction (RT-PCR) assays are the most widely used molecular tests for the detection of SARS-CoV-2 and diagnosis of COVID-19 in clinical samples. PCR assays target unique genomic RNA regions to identify SARS-CoV-2 with high sensitivity and specificity....

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Bibliographic Details
Main Authors: Daniel Antonio Negrón, June Kang, Shane Mitchell, Mitchell Y. Holland, Stephen Wist, Jameson Voss, Lauren Brinkac, Katharine Jennings, Stephanie Guertin, Bruce G. Goodwin, Shanmuga Sozhamannan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Public Health
Subjects:
PCR
RT-PCR
COVID-19
SARS-CoV-2
diagnostics
pandemic
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.889973/full

Internet

https://www.frontiersin.org/articles/10.3389/fpubh.2022.889973/full

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