GPCR Inhibitors Have Antiviral Properties against JC Polyomavirus Infection

GPCR Inhibitors Have Antiviral Properties against JC Polyomavirus Infection

JC polyomavirus (JCPyV) infects the majority of the population and initially establishes a persistent but asymptomatic infection of the kidneys. In healthy individuals, the infection remains controlled by the host immune system, but for individuals experiencing prolonged immunosuppression, the infec...

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Bibliographic Details
Main Authors: Amanda L. Sandberg, Avery C. S. Bond, Lucas J. Bennett, Sophie E. Craig, David P. Winski, Lara C. Kirkby, Abby R. Kraemer, Kristina G. Kelly, Samuel T. Hess, Melissa S. Maginnis
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Viruses
Subjects:
JC polyomavirus
progressive multifocal leukoencephalopathy
PML
GPCR agonists/antagonists
cetirizine
paroxetine
Online Access:https://www.mdpi.com/1999-4915/16/10/1559

Internet

https://www.mdpi.com/1999-4915/16/10/1559

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