The anti-staphylococcal fusidic acid as an efflux pump inhibitor combined with fluconazole against vaginal candidiasis in mouse model

The anti-staphylococcal fusidic acid as an efflux pump inhibitor combined with fluconazole against vaginal candidiasis in mouse model

Abstract Background Candida albicans is the most common fungus that causes vaginal candidiasis in immunocompetent women and catastrophic infections in immunocompromised patients. The treatment of such infections is hindered due to the increasing emergence of resistance to azoles in C. albicans. New...

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Bibliographic Details
Main Authors: Salwa E. Gomaa, Hisham A. Abbas, Fatma A. Mohamed, Mohamed A. M. Ali, Tarek M. Ibrahim, Alyaa S. Abdel Halim, Mashael A. Alghamdi, Basem Mansour, Anis Ahmad Chaudhary, Amr Elkelish, Fehmi Boufahja, Wael A. H. Hegazy, Fatma Al-zahraa A. Yehia
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Microbiology
Subjects:
Drug repurposing
Vaginal candidiasis
Fluconazole resistant Candida albicans
Fusidic acid
Efflux pumps
Online Access:https://doi.org/10.1186/s12866-024-03181-z

Internet

https://doi.org/10.1186/s12866-024-03181-z

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