Development of three-dimensional articular cartilage construct using silica nano-patterned substrate.

Current strategies for cartilage cell therapy are mostly based on the use of autologous chondrocytes. However, these cells have limitations of a small number of cells available and of low chondrogenic ability, respectively. Many studies now suggest that fetal stem cells are more plastic than adult s...

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Bibliographic Details
Main Authors: In-Su Park, Ye Ji Choi, Hyo-Sop Kim, Sang-Hyug Park, Byung Hyune Choi, Jae-Ho Kim, Bo Ram Song, Byoung-Hyun Min
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208291