Salinomycin biosynthesis reversely regulates the β‐oxidation pathway in Streptomyces albus by carrying a 3‐hydroxyacyl‐CoA dehydrogenase gene in its biosynthetic gene cluster

Abstract Streptomyces is well known for synthesis of many biologically active secondary metabolites, such as polyketides and non‐ribosomal peptides. Understanding the coupling mechanisms of primary and secondary metabolism can help develop strategies to improve secondary metabolite production in Str...

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Bibliographic Details
Main Authors: Jiaxiu Wei, Binbin Chen, Jianxin Dong, Xueyu Wang, Yongquan Li, Yingchun Liu, Wenjun Guan
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.14145