Effect of a High-Fat Diet on the Small-Intestinal Environment and Mucosal Integrity in the Gut-Liver Axis

Effect of a High-Fat Diet on the Small-Intestinal Environment and Mucosal Integrity in the Gut-Liver Axis

Although high-fat diet (HFD)-related dysbiosis is involved in the development of steatohepatitis, its pathophysiology especially in the small intestine remains unclear. We comprehensively investigated not only the liver pathology but also the microbiome profile, mucosal integrity and luminal environ...

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Bibliographic Details
Main Authors: Takashi Nakanishi, Hirokazu Fukui, Xuan Wang, Shin Nishiumi, Haruka Yokota, Yutaka Makizaki, Yoshiki Tanaka, Hiroshi Ohno, Toshihiko Tomita, Tadayuki Oshima, Hiroto Miwa
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
high-fat diet
small intestine
microbiome
bile acid
barrier
Online Access:https://www.mdpi.com/2073-4409/10/11/3168

Internet

https://www.mdpi.com/2073-4409/10/11/3168

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