Crosstalk and plasticity driving between cancer-associated fibroblasts and tumor microenvironment: significance of breast cancer metastasis

Abstract Cancer-associated fibroblasts (CAFs) are the most abundant stromal cell population in breast tumors. A functionally diverse population of CAFs increases the dynamic complexity of the tumor microenvironment (TME). The intertwined network of the TME facilitates the interaction between activat...

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Bibliographic Details
Main Authors: Wenfeng Zhang, Jia Wang, Cun Liu, Ye Li, Changgang Sun, Jibiao Wu, Qibiao Wu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04714-2