Absence of protoheme IX farnesyltransferase CtaB causes virulence attenuation but enhances pigment production and persister survival in MRSA
The membrane protein CtaB in S. aureus is a protoheme IX farnesyltransferase, involved in the synthesis of the heme containing terminal oxidases of bacterial respiratory chain. In this study, to assess the role of CtaB in S. aureus virulence, pigment production, and persister formation, we construct...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-10-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01625/full |