Salmonella and Caspase-1: a complex interplay of detection and evasion

Salmonellae are intracellular pathogens that replicate within epithelial cells and macrophages, and are a significant public health threat in both developed and developing countries. The innate immune system detects microbes through pattern recognition receptors, which are compartmentalized on the...

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Bibliographic Details
Main Authors: Edward A Miao, Jayant V Rajan
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00085/full