Higher levels of Pseudomonas aeruginosa LasB elastase expression are associated with early-stage infection in cystic fibrosis patients

Abstract Pseudomonas aeruginosa is a common pathogen in cystic fibrosis (CF) patients and a major contributor to progressive lung damage. P. aeruginosa elastase (LasB), a key virulence factor, has been identified as a potential target for anti-virulence therapy. Here, we sought to differentiate the...

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Bibliographic Details
Main Authors: Agustina Llanos, Pauline Achard, Justine Bousquet, Clarisse Lozano, Magdalena Zalacain, Carole Sable, Hélène Revillet, Marlène Murris, Marie Mittaine, Marc Lemonnier, Martin Everett
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41333-9