Efficacy of PARP inhibitor therapy after targeted BRAF/MEK failure in advanced melanoma

Abstract Modern advancements in targeted therapy and immunotherapy have significantly improved survival outcomes for advanced melanoma; however, there remains a need for novel approaches to overcome disease progression and treatment resistance. In recent years, PARPi therapy has shown great promise...

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Bibliographic Details
Main Authors: Jordan Phillipps, George Nassief, Renee Morecroft, Tolulope Adeyelu, Andrew Elliott, Farah Abdulla, Ari Vanderwalde, Soo Park, Omar Butt, Alice Zhou, George Ansstas
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00684-w