Centrosome Dynamics and Its Role in Inflammatory Response and Metastatic Process

Centrosome Dynamics and Its Role in Inflammatory Response and Metastatic Process

Metastasis is a process by which cancer cells escape from the location of the primary tumor invading normal tissues at distant organs. Chromosomal instability (CIN) is a hallmark of human cancer, associated with metastasis and therapeutic resistance. The centrosome plays a major role in organizing t...

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Bibliographic Details
Main Authors: Massimo Pancione, Luigi Cerulo, Andrea Remo, Guido Giordano, Álvaro Gutierrez-Uzquiza, Paloma Bragado, Almudena Porras
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
centrosome
chromosome instability
Rho GTPases
p38 MAPK
tumor microenvironment
Online Access:https://www.mdpi.com/2218-273X/11/5/629

Internet

https://www.mdpi.com/2218-273X/11/5/629

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