QTc interval and ventricular action potential prolongation in the Mecp2Null/+ murine model of Rett syndrome

Abstract Rett Syndrome (RTT) is a congenital, X‐chromosome‐linked developmental disorder characterized by developmental delay, dysautonomia, and breathing irregularities. RTT is also associated with sudden death and QT intervals are prolonged in some RTT patients. Most individuals with RTT have muta...

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Bibliographic Details
Main Authors: Hongwei Cheng, Ian Charles, Andrew F. James, Ana P. Abdala, Jules C. Hancox
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15437