Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes.
BACKGROUND:The insulin receptor is localized in caveolae and is dependent on caveolae or cholesterol for signaling in adipocytes. When stimulated with insulin, the receptor is internalized. METHODOLOGY/PRINCIPAL FINDINGS:We examined primary rat adipocytes by subcellular fractionation to examine if t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-06-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2695004?pdf=render |