IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations.

IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations.

BACKGROUND: Interleukin 4 (IL-4) is an anti-inflammatory cytokine, which regulates balance between T(H)1 and T(H)2 immune response, immunoglobulin class switching and humoral immunity. Polymorphisms in this gene have been reported to affect the risk of infectious and autoimmune diseases. METHODS: We...

Full description

Bibliographic Details
Main Authors: Aditya Nath Jha, Vipin Kumar Singh, Namrata Kumari, Ashish Singh, Justin Antony, Hoang van Tong, Sakshi Singh, Sudhanshu S Pati, Pradeep K Patra, Rajender Singh, Nguyen L Toan, Le H Song, Amal Assaf, Iara J T Messias-Reason, Thirumalaisamy P Velavan, Lalji Singh, Kumarasamy Thangaraj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480467?pdf=render

Internet

http://europepmc.org/articles/PMC3480467?pdf=render

Similar Items