A comparison of the whole genome approach of MeDIP-seq to the targeted approach of the Infinium HumanMethylation450 BeadChip(®) for methylome profiling.

DNA methylation is one of the most studied epigenetic marks in the human genome, with the result that the desire to map the human methylome has driven the development of several methods to map DNA methylation on a genomic scale. Our study presents the first comparison of two of these techniques - th...

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Bibliographic Details
Main Authors: Christine Clark, Priit Palta, Christopher J Joyce, Carol Scott, Elin Grundberg, Panos Deloukas, Aarno Palotie, Alison J Coffey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3510246?pdf=render