Spatiotemporal control of genome engineering in cone photoreceptors

Spatiotemporal control of genome engineering in cone photoreceptors

Abstract Background Cones are essential for color recognition, high resolution, and central vision; therefore cone death causes blindness. Understanding the pathophysiology of each cell type in the retina is key to developing therapies for retinal diseases. However, studying the biology of cone cell...

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Bibliographic Details
Main Authors: Nan-Kai Wang, Pei-Kang Liu, Yang Kong, Yun-Ju Tseng, Laura A. Jenny, Nicholas D. Nolan, Nelson Chen, Hung-Hsi Wang, Chun Wei Hsu, Wan-Chun Huang, Janet R. Sparrow, Chyuan-Sheng Lin, Stephen H. Tsang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell & Bioscience
Subjects:
Cone arrestin
Arrestin 3
Cre-LoxP recombination
CreERT2
2A peptide
Online Access:https://doi.org/10.1186/s13578-023-01033-3

Internet

https://doi.org/10.1186/s13578-023-01033-3

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